RDB Clones in Publications

When you publish your research results in a scientific journal, please refer to the origin of materials that were provided from RIKEN BRC and used in your research subject. We appreciate your cooperation.
Example :
________ (name of BIOLOGICAL RESOURCE) was provided by RIKEN BRC which is participating in the National Bio-Resource Project of the MEXT, Japan.

Journal publication

Patent publication

↑ 2010 ↓
RDB No.	Title	Journal	Author	PMID
(1890) pRx-crmA-bsr	Tumor necrosis factor-related apoptosis-inducing ligand 1 (TRAIL1) enhances the transition of red blood cells from the larval to adult type during metamorphosis in Xenopus.	Blood 115 (4): 850-859 (2010).	Tamura, K., Mawaribuchi, S., Yoshimoto, S., Shiba, T., Takamatsu, N., Ito, M.	19965624

↑ 2009 ↓
RDB No.	Title	Journal	Author	PMID
(6284) T. thermophilus HB8 Disruption Plasmid TTHA1619	N7-Methylguanine at position 46 (m7G46) in tRNA from Thermus thermophilus is required for cell viability at high temperatures through a tRNA modification network.	Nucleic Acids Res. 2009 Nov 24. [Epub ahead of print] (2009).	Tomikawa, C., Yokogawa, T., Kanai, T., Hori, H.	19934251
(1862) pCALNL5	Mature acinar cells are refractory to carcinoma development by targeted activation of Ras oncogene in adult rats.	Cancer Sci. 2009 Oct 22. [Epub ahead of print] (2009).	Tanaka, H., Fukamachi, K., Futakuchi, M., Alexander, D.B., Long, N., Tamamushi, S., Minami, K., Seino, S., Ohara, H., Joh, T., Tsuda, H.	19917056
(1862) pCALNL5	An animal model of preclinical diagnosis of pancreatic ductal adenocarcinomas.	Biochem. Biophys. Res. Commun. 390 (3): 636-641 (2009).	Fukamachi, K., Tanaka, H., Hagiwara, Y., Ohara, H., Joh, T., Iigo, M., Alexander, D.B., Xu, J., Long, N., Takigahira, M., Yanagihara, K., Hino, O., Saito, I., Tsuda, H.	19818733
(5820) S. pombe ORFeome clone SPCC825.02 (26/D11) (6151) pDUAL-YFH1c (6519) pREP1-ccdB2	Glucosidase II beta subunit modulates N-glycan trimming in fission yeasts and mammals.	Mol. Biol. Cell 20 (17): 3974-3984 (2009).	Stigliano, I.D., Caramelo, J.J., Labriola, C.A., Parodi, A.J., D'Alessio, C.	19605557
(4214) MSM/Ms Mouse BAC clones & library MSMg01-529G05	Visualization of chemokine receptor activation in transgenic mice reveals peripheral activation of CCR2 receptors in states of neuropathic pain.	J. Neurosci. 29 (25): 8051-8062 (2009).	Jung, H., Bhangoo, S., Banisadr, G., Freitag, C., Ren, D., White, F.A., Miller, R.J.	19553445
(1687) pCM-hGM	Quick method of multimeric protein production for biologically active substances such as human GM-CSF (hGM-CSF).	Biochem. Biophys. Res. Commun. 386 (1): 40-44 (2009).	Shinya, E., Owaki, A., Norose, Y., Sato, S., Takahashi, H.	19497303
(5616) pSTAT RE-TK hRluc(F) (5610) pISRE-TK hRluc(F) (5624) pGAS RE-TK hRluc(F)	Chondromodulin-1 directly suppresses growth of human cancer cells.	BMC Cancer 9: 166 (2009).	Mera, H., Kawashima, H., Yoshizawa, T., Ishibashi, O., Ali, M.M., Hayami, T., Kitahara, H., Yamagiwa, H., Kondo, N., Ogose, A., Endo, N., Kawashima, H.	19480713
(4214) MSM/Ms Mouse BAC clones & library MSMg01-414M07	Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests.	Nat. Genet. 41: 688 - 695 (2009).	Tomida, S., Mamiya, T., Sakamaki, H., Miura, M., Aosaki, T., Masuda. M., Niwa, M., Kameyama, T., Kobayashi, J., Iwaki, Y., Imai, S., Ishikawa, A., Abe, K., Yoshimura, T., Nabeshima, T., Ebihara, S.	19465912
(1735) Ax1 CI-mIGIF	Cytosine deaminase-uracil phosphoribosyltransferase and interleukin (IL)-12 and IL-18: a multimodal anticancer interface marked by specific modulation in serum cytokines.	Clin. Cancer Res. 15 (7): 2323-2334 (2009).	Khatri, A., Husaini, Y., Ow, K., Chapman, J., Russell, P.J.	19318483
(1476) pBluescript SKII+mIL10	Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco.	BMC Biotechnol. 9: 22 (2009).	Bortesi, L., Rossato, M., Schuster, F., Raven, N., Stadlmann, J., Avesani, L., Falorni, A., Bazzoni, F., Bock, R., Schillberg, S., Pezzotti, M.	19298643
(2199) AxCAhFLIP	Adenovirus-mediated gene expression of the human c-FLIP(L) gene protects pig islets against human CD8(+) cytotoxic T lymphocyte-mediated cytotoxicity.	Transplant. Proc. 41 (1): 319-322 (2009).	Tanemura, M., Saga, A., Kawamoto, K., Machida, T., Deguchi, T., Nishida, T., Sawa, Y., Doki, Y., Mori, M., Ito, T.	19249545
(5808) pBMSA-PB2	Crystallization and X-ray diffraction analysis of the RNA primer/promoter-binding domain of influenza A virus RNA-dependent RNA polymerase PB2.	Acta Crystallogr. Sect. F. Struct. Biol. Cryst. Commun. 65 (Pt 2): 144-146 (2009).	Kuzuhara, T., Kise, D., Yoshida, H., Horita, T., Murazaki, Y., Utsunomiya, H., Tsuge, H.	19194006
(5808) pBMSA-PB2	Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue.	J. Biol. Chem. 284 (11): 6855-6860 (2009).	Kuzuhara, T., Kise, D., Yoshida, H., Horita, T., Murazaki, Y., Nishimura, A., Echigo, N., Utsunomiya, H., Tsuge, H.	19144639
(4214) MSM/Ms Mouse BAC clones & library	Transcriptional regulation of fibrillin-2 gene by E2F family members in chondrocyte differentiation.	J. Cell. Biochem. 106 (4): 580-588 (2009).	Yanagino, T., Yuasa, K., Nagahama, M., Matsuda, Y., Tsuji, A.	19142862
(6078) Thermus thermophilus expression plasmids TTHA0132 TTHA0271 TTHA0281 TTHA0341 TTHA1053 TTHA1091 TTHA1199 TTHA1275 TTHA1359 TTHA1671 TTHA1699 TTHA1713 TTHA1838 TTHA1897 TTHB192	Thermus thermophilus-derived protein tags that aid in preparation of insoluble viral proteins.	Anal. Biochem. 385 (2): 278-285 (2009).	Kondo, N., Ebihara, A., Ru, H., Kuramitsu, S., Iwamoto, A., Rao, Z., Matsuda, Z.	19084492
(5463) DNA clone pBC-H2.6	qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin.	Antimicrob. Agents. Chemother. 53 (2): 603-608 (2008).	Cavaco, L.M., Hasman, H., Xia, S., Aarestrup, F.M.	19029321
(1579) AxCEAprZ (2547) AxCAHSVtk (2726) AxCALacZ (1746) Ax1w1 (1578) AxCEAprTK	E1A, E1B double-restricted replicative adenovirus at low dose greatly augments tumor-specific suicide gene therapy for gallbladder cancer.	Cancer Gene Ther. 16 (2): 126-136 (2009).	Fukuda, K., Abei, M., Ugai, H., Kawashima, R., Seo, E., Wakayama, M., Murata, T., Endo, S., Hamada, H., Hyodo, I., Yokoyama, K.K.	18818710

↑ 2008 ↓
RDB No.	Title	Journal	Author	PMID
(1184) Mouse E-cadherin full length cDNA	Interaction of KLRG1 with E-cadherin: new functional and structural insights.	Eur. J. Immunol. 38 (12): 3354-3364 (2008).	Rosshart, S., Hofmann, M., Schweier, O., Pfaff, A.K., Yoshimoto, K., Takeuchi, T., Molnar, E., Schamel, W.W., Pircher, H.	19009530
(1862) pCALNL5	Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain.	Proc. Natl. Acad. Sci. U. S. A. 105 (46): 18012-18017 (2008).	Kohyama, J., Kojima, T., Takatsuka, E., Yamashita, T., Namiki, J., Hsieh, J., Gage, F.H., Namihira, M., Okano, H., Sawamoto, K., Nakashima, K.	19004774
(3452) p3AP1 (PMA) RE-TK hRluc(F)	p63/p51-induced onset of keratinocyte differentiation via the c-Jun N-terminal kinase pathway is counteracted by keratinocyte growth factor.	J Biol Chem. 283 (49): 34241-34249 (2008).	Ogawa E, Okuyama R, Egawa T, Nagoshi H, Obinata M, Tagami H, Ikawa S, Aiba S.	18849344
(1038) pUCAlu	Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres.	Genes Cells. 13 (10): 1045-1059 (2008).	Tatsumi, Y., Ezura, K., Yoshida, K., Yugawa, T., Narisawa-Saito, M., Kiyono, T., Ohta, S., Obuse, C., Fujita, M.	18761675
(2774) AxCArJunB (forward)	JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells.	PLoS One. 3 (8): e3030 (2008).	Gurzov, E.N., Ortis, F., Bakiri, L., Wagner, E.F, Eizirik, D.L.	18716665
(1678) pAxCAwt	Ramified microglial cells promote astrogliogenesis and maintenance of neural stem cells through activation of Stat3 function.	FASEB J. 22 (11): 3866-3877 (2008).	Zhu, P., Hata, R., Cao, F., Gu, F., Hanakawa, Y., Hashimoto, K., Sakanaka, M.	18685078
(3459) phRL-3CRE-TK	IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcription.	FEBS Lett. 582 (19): 2833-2837 (2008).	Kimura, M.	18671972
(1184) Mouse E-cadherin full length cDNA	Enhancement of cell function through heterotypic cell-cell interactions using E-cadherin-expressing NIH3T3 cells.	J Biosci Bioeng. 105 (6): 679-682 (2008).	Ito, A., Kiyohara, T., Kawabe, Y., Ijima, H., Kamihira, M.	18640611
(1184) Mouse E-cadherin full length cDNA	Design of the artificial acellular feeder layer for the efficient propagation of mouse embryonic stem cells.	J. Biol. Chem. 283 (39): 26468-26476 (2008).	Nagaoka, M., Hagiwara, Y., Takemura, K., Murakami, Y., Li, J., Duncan, S.A., Akaike, T.	18614540
(1201) pIL-2R gamma 2	Selective expansion of genetically modified T cells using an antibody/interleukin-2 receptor chimera.	J. Immunol. Methods 337 (1): 16-23 (2008).	Sogo, T., Kawahara, M., Tsumoto, K., Kumagai, I., Ueda, H., Nagamune, T.	18589435
(1126) pSVtsA58 ori (-)	Different initial steps of apoptosis induced by two types of antineoplastic drugs.	Biochem. Pharmacol.76 (3): 303-311 (2008).	Takagi, Y., Hidaka, M., Sanada, M., Yoshida, H., Sekiguchi, M.	18573489
(1198) ETR103	Covalent split protein fragment-DNA hybrids generated through N-terminus-specific modification of proteins by oligonucleotides.	Org. Biomol. Chem. 6 (12): 2187-2194 (2008).	Takeda, S., Tsukiji, S., Ueda, H., Nagamune, T.	18528581
(1785) pcDNA3-XPF	Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair.	Cancer Res. 68 (10): 3881-3889 (2008).	Wang, Y., Liu, X., Matsuda, A., Plunkett, W.	18483273
()	Zfp64 participates in Notch signaling and regulates differentiation in mesenchymal cells.	J. Cell Sci. 121 (Pt 10): 1613-1623 (2008).	Sakamoto, K., Tamamura, Y., Katsube, K., Yamaguchi, A.	18430783
(1372) Human MDR1 cDNA	Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs.	Pharmacogenet. Genomics 18 (5): 390-402 (2008).	Hung, C.C., Chen, C.C., Lin, C.J., Liou, H.H.	18408562
(1862) pCALNL5	Oocyte-specific overexpression of mouse bone morphogenetic protein-15 leads to accelerated folliculogenesis and an early onset of acyclicity in transgenic mice.	Endocrinology 149 (6): 2807-2815 (2008).	McMahon, H.E., Hashimoto, O., Mellon, P.L., Shimasaki, S.	18308851
(4757) pGST-mmJDP2_full (4778) pGST-mmJDP2_T148A (6211) pT7Tet1 (6216) pET_His-hsJDP2 (6321) pET_HisFLAG-hsATF-2 (6793) H3002E12	Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in Escherichia coli by Jun N-terminal kinase 1.	Anal. Biochem. 376 (1): 115-121 (2008).	Murata T., Shinozuka Y., Obata Y., Yokoyama K.K.	18307971
(5463) pBC-H2.6	Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan.	Antimicrob. Agents Chemother. 52 (4): 1564-1566 (2008).	Yamane, K., Wachino, J., Suzuki, S., Arakawa, Y.	18285488
(1487) pBluescript SKII+mbFGF	Construction of adeno-associated virus system for human bone morphogenetic protein 7 gene.	J. Huazhong Univ. Sci. Technolog. Med. Sci.28 (1): 17-21 (2008).	Song, K., Rao, N., Chen, M., Cao, Y.	18278449
(1198) ETR103	Dimerization-based homogeneous fluorosensor proteins for the detection of specific dsDNA.	Biosens. Bioelectron. 23 (8): 1266-1271 (2008).	Yoshitake K., Waki S., Ueda H.	18178076
(3219) pCMV-MAZ (4267)pCMV-Sp1	Characterization of a neuregulin-1 gene promoter: positive regulation of type I isoforms by NF-kappaB.	Biochim. Biophys. Acta 1779 (2): 139-144 (2008).	Frensing, T., Kaltschmidt, C., Schmitt-John, T.	18082154
(1524) pCAhMCSF	Identification of angiogenin as the osteoclastic bone resorption-inhibitory factor in bovine milk.	Bone 42 (2): 380-387 (2008).	Morita, Y., Matsuyama, H., Serizawa, A., Takeya, T., Kawakami, H.	18055286
(1410) AxCAmIL10	Interleukin-10 gene transfer to peritoneal mesothelial cells suppresses peritoneal dissemination of gastric cancer cells due to a persistently high concentration in the peritoneal cavity.	Cancer Gene Ther. 15 (1): 51-59 (2008).	Tanaka F., Tominaga K., Shiota M., Ochi M., Kuwamura H., Tanigawa T., Watanabe T., Fujiwara Y., Oshitani N., Higuchi K., Iwao H., Arakawa T.	17992202
(4214) MSM/Ms Mouse BAC clones & library MSMg01-529G05	Monocyte chemoattractant protein-1 functions as a neuromodulator in dorsal root ganglia neurons.	J. Neurochem. 104 (1): 254-263. (2008).	Jung, H., Toth, P.T., White, F.A., Miller, R.J.	17944871

↑ 2007 ↓
RDB No.	Title	Journal	Author	PMID
(4214) MSM/Ms Mouse BAC clones & library MSMg01-121H09 MSMg01-379H11 MSMg01-090M04 MSMg01-528J16 MSMg01-412N17 MSMg01-342I20	Emergence of complex rearrangements at translocation breakpoints in a transgenic mouse; implications for mechanisms involved in the formation of chromosome rearrangements.	Cytogenet. Genome Res. 119 (1-2): 83-90 (2007).	Kasai, F., Yoshihara, M., Matsukuma, S., O'Brien, P., Ferguson-Smith, M.A.	18160786
(1171) pKCR. Tac-2A	A dileucine motif in its cytoplasmic domain directs beta-catenin-uncoupled E-cadherin to the lysosome.	J. Cell Sci. 120 (Pt 24): 4395-4406 (2007).	Miyashita, Y., Ozawa, M.	18057030
(2013) pAxCAhPTEN1	Transduction of phosphatase and tensin homolog deleted on chromosome 10 into eosinophils attenuates survival, chemotaxis, and airway inflammation.	J. Immunol. 179 (12): 8105-8111 (2007).	Adachi, T., Hanaka, S., Masuda, T., Yoshihara, H., Nagase, H., Ohta, K.	18056352
(1746) Ax1w1	Thrombin-induced cell proliferation and platelet-derived growth factor-AB release from A172 human glioblastoma cells.	J. Thromb. Haemost. 5 (11): 2219-2226 (2007).	Hayakawa, Y., Kurimoto, M., Nagai, S., Kurosaki, K., Tsuboi, Y., Hamada, H., Hayashi, N., Endo, S.	17958740
(1737) Ax1 CMhIL4 (2203) AxCMTK/R	Expression of pIX gene induced by transgene promoter: possible cause of host immune response in first-generation adenoviral vectors.	Hum. Gene Ther. 18 (10): 925-936 (2007).	Nakai M., Komiya K., Murata M., Kimura T., Kanaoka M., Kanegae Y., Saito I.	17907966
(5463) DNA clone pBC-H2.6	Plasmid-mediated quinolone resistance determinant qnrS1 detected in Salmonella enterica serovar Corvallis strains isolated in Denmark and Thailand.	J. Antimicrob. Chemother. 60 (3): 704-706 (2007).	Cavaco LM, Hendriksen RS, Aarestrup FM.	17635876
(5616) pSTAT RE-TK hRluc(F) (5610) pISRE-TK hRluc(F) (5624) pGAS RE-TK hRluc(F)	PIASxbeta is a key regulator of osterix transcriptional activity and matrix mineralization in osteoblasts.	J. Cell Sci. 120 (Pt 15): 2565-2573 (2007).	Ali, M.M., Yoshizawa, T., Ishibashi, O., Matsuda, A., Ikegame, M., Shimomura, J., Mera, H., Nakashima, K., Kawashima, H.	17623776
(1748) AxCANCre (3211) AxCANLacZ	Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure.	Proc. Natl. Acad. Sci. U S A. 104 (25): 10703-10708 (2007).	Dali-Youcef N., Mataki C., Coste A., Messaddeq N., Giroud S., Blanc S., Koehl C., Champy M.F., Chambon P., Fajas L., Metzger D., Schoonjans K., Auwerx J.	17556545
(2194) AxCAZ3-F/RGD (2726) AxCALacZ (1746) Ax1w1	E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers.	Clin. Cancer Res. 13 (10): 3043-3050 (2007).	Wakayama M., Abei M., Kawashima R., Seo E., Fukuda K., Ugai H., Murata T., Tanaka N., Hyodo I., Hamada H., Yokoyama K.K.	17505007
(2726) AxCALacZ	JDP2 suppresses adipocyte differentiation by regulating histone acetylation.	Cell Death Differ. 14 (8): 1398-1405 (2007).	Nakade K., Pan J., Yoshiki A., Ugai H., Kimura M., Liu B., Li H., Obata Y., Iwama M., Itohara S., Murata T., Yokoyama K.K.	17464331
(1126) pSVtsA58 ori (-)	Identification of genetic networks involved in the cell growth arrest and differentiation of a rat astrocyte cell line RCG-12.	J. Cell Biochem. 15;102 (6): 1472-1485 (2007).	Takasaki, I., Takarada, S., Fukuchi, M., Yasuda, M., Tsuda, M., Tabuchi, Y.	17440958
(1870) pCAZ 2	The administration of naked plasmid DNA into the liver induces antitumor innate immunity in a murine liver metastasis model.	J. Gene Med. 9 (4): 299-307 (2007).	Yonenaga Y., Mori A., Fujimoto A., Nagayama S., Tachibana T., Onodera H., Uemoto S.	17397091
(5463) DNA clone pBC-H2.6	First detection of plasmid-mediated quinolone resistance (qnrA and qnrS) in Escherichia coli strains isolated from humans in Scandinavia.	J. Antimicrob. Chemother. 59 (4): 804-805 (2007).	Cavaco LM, Hansen DS, Friis-Moller A, Aarestrup FM, Hasman H, Frimodt-Moller N.	17284539
(2012) AxCAhPTEN1	PTEN reduces cuff-induced neointima formation and proinflammatory cytokines.	Am J Physiol Heart Circ Physiol. 292 (6): H2824-H2831 (2007).	Koide S., Okazaki M., Tamura M., Ozumi K., Takatsu H., Kamezaki F., Tanimoto A., Tasaki H., Sasaguri Y., Nakashima Y., Otsuji Y.	17277022
(1748) AxCANCre	Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.	J. Biol. Chem. 282 (14): 10138-10145 (2007).	Tomimatsu N., Tahimic C.G., Otsuki A., Burma S., Fukuhara A., Sato K., Shiota G., Oshimura M., Chen D.J., Kurimasa A.	17272272
(3022) pCMX-N/RBP-J (R218H)	Notch Ligand Delta-Like 1 Is Essential for Postnatal Arteriogenesis.	Circulation Research. 100 (3): 363-371 (2007).	Limbourg A., Ploom M., Elligsen D., Sorensen I., Ziegelhoeffer T., Gossler A., Drexler H., Limbourg F.P.	17234965
(2925) Nojima cDNA Library Collection No.35, S. cerevisiae, S288C (Log)	Interactions between peptides containing nucleobase amino acids and T7 phages displaying S. cerevisiae proteins.	Biopolymers 88 (2): 131-140 (2007).	Watanabe, S., Tomizaki, K.Y., Takahashi, T., Usui, K., Kajikawa, K., Mihara, H.	17206624

↑ 2006 ↓
RDB No.	Title	Journal	Author	PMID
(1184) Mouse E-cadherin full length cDNA	E-cadherin-coated plates maintain pluripotent ES cells without colony formation.	PLoS One. 1: e15 (2006).	Nagaoka, M., Koshimizu, U., Yuasa, S., Hattori, F., Chen, H., Tanaka, T., Okabe, M., Fukuda, K., Akaike, T.	17183641
(1801) RBP-J (3022) pCMX-N/RBP-J (R218H) (3023) pCMX-N/VP16-RBP-J	Canonical notch signaling functions as a commitment switch in the epidermal lineage.	Genes Dev. 20 (21): 3022-3035 (2006).	Blanpain, C., Lowry, W.E., Pasolli, H.A., Fuchs, E.	17079689
(2012) AxCAhPTEN1 (2726) AxCALacZ	Suppression of PTEN expression during aggregation with retinoic acid in P19 mouse embryonal carcinoma cells.	Biochem Biophys Res Commun. 347 (3): 715-722 (2006).	Lee JH, Shin SY, Kim S, Choo J, Lee YH.	16842746
(1678) pAxCAwt	Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells.	J. Neurochem., 98, 459-447 (2006).	Cao F., Hata R., Zhu P., Ma Y.J., Tanaka J., Hanakawa Y., Hashimoto K., Niinobe M., Yoshikawa K., Sakanaka M.	16805839
(1748) AxCANCre	The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development.	Development 133, 3005-3013. (2006).	Sakaki-Yumoto M., Kobayashi C., Sato A., Fujimura S., Matsumoto Y., Takasato M., Kodama T., Aburatani H., Asashima M., Yoshida N., Nishinakamura R.	16790473
(1674) pCALNLw	Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas.	Carcinogenesis, 27, 2497-2510 (2006).	Ueda S., Fukamachi K., Matsuoka Y., Takasuka N., Takeshita F., Naito A., Iigo M., Alexander D.B., Moore M.A., Saito I., Ochiya T., Tsuda H.	16774944
(2354) pEF-Flag-mSTATY705F	Mouse model of human infertility: transient and local inhibition of endometrial STAT-3 activation results in implantation failure.	FEBS Lett. 580 (11): 2717-2722 (2006).	Nakamura, H., Kimura, T., Koyama, S., Ogita, K., Tsutsui, T., Shimoya, K., Taniguchi, T., Koyama, M., Kaneda, Y., Murata, Y.	16647058
(1679) pCALwL	Transgenic mouse for conditional, tissue-specific Cox-2 overexpression.	Genesis 44 (4): 177-182 (2006).	Kamei, K., Ishikawa, T.O., Herschman, H.R.	16604526
(1414) AxCAmIL12p35 (1417) AxCAmIL12p40	The boosting effect of co-transduction with cytokine genes on cancer vaccine therapy using genetically modified dendritic cells expressing tumor-associated antigen.	Int. J. Oncol., 28, 947-953 (2006).	Ojima T., Iwahashi M., Nakamura M., Matsuda K., Naka T., Nakamori M., Ueda K., Ishida K., Yamaue H.	16525645
(4757) pGST-mmJDP2_full (4755) pcDNA4-mmJDP2_wt	Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2.	Nat. Struct. Mol. Biol., 13, 331-338 (2006).	Jin C., Kato K., Chimura T., Yamasaki T., Nakade K., Murata T., Li H., Pan J., Zhao M., Sun K., Chiu R., Ito T., Nagata K., Horikoshi M., Yokoyama K.K.	16518400
(2012) AxCAhPTEN1	Suppression of Egr-1 transcription through targeting of the serum response factor by oncogenic H-Ras.	EMBO J. 25 (5): 1093-1103 (2006).	Shin SY, Bahk YY, Ko J, Chung IY, Lee YS, Downward J, Eibel H, Sharma PM, Olefsky JM, Kim YH, Lee B, Lee YH.	16456537
(1960) pGMT20	A Novel Yeast-Based Reporter Assay System for the Sensitive Detection of Genotoxic Agents Mediated by a DNA Damage-Inducible LexA-GAL4 Protein.	J. Biochem. (Tokyo)., 139, 105-112 (2006).	Ichikawa K., Eki T.	16428325
(1184) Mouse E-cadherin full length cDNA	Cutting edge: identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1.	J. Immunol. 176 (3): 1311-5131 (2006).	Grundemann C., Bauer M., Schweier O., von Oppen N., Lassing U., Saudan P., Becker K.F., Karp K., Hanke T., Bachmann M.F., Pircher H.	16424155
(2410) AxCALNLrmaf2 (1748) AxCANCre	Activation of connective tissue growth factor gene by the c-Maf and Lc-Maf transcription factors.	Biochem. Biophys. Res. Commun., 339, 1089-1097 (2006).	Omoteyama K., Ikeda H., Imaki J., Sakai M.	16343439
(2355) pEF-NFIL6	CCAAT/enhancer binding protein beta binds to and activates the P670 promoter of human papillomavirus type 16.	Virology, 346: 98-107 (2006).	Kukimoto I., Takeuchi T., Kanda T.	16307770

↑ 2005 ↓
RDB No.	Title	Journal	Author	PMID
(2355) pEF-NFIL6	The role of pit-1 in the regulation of the rat growth hormone-releasing hormone receptor gene transcription by glucocorticoids.	J. Mol. Endocrinol., 35, 477-488 (2005).	Nogami H., Hiraoka Y., Ogasawara K., Aiso S., Hisano S.	16326834
(2443) pCAcc-Luc+	Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer.	Nat. Mater., 4, 934-941 (2005).	Nishiyama N., Iriyama A., Jang W.D., Miyata K., Itaka K., Inoue Y., Takahashi H., Yanagi Y., Tamaki Y., Koyama H., Kataoka K.	16299510
(1747) Ad5-dlX and others	Accumulation of infectious mutants in stocks during the propagation of fiber-modified recombinant adenoviruses.	Biochem. Biophys. Res. Commun. 337, 806-814 (2005).	Ugai H., Inabe K., Yamasaki T., Murata T., Obata Y., Hamada H., Yokoyama K.K.	16214112
(2004) AxCALNLBcl2a (1748) AxCANCre	Mitochondrial impairment induced by poly(ADP-ribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation.	J. Neurochem., 95, 179-190 (2005).	Tanaka S., Takehashi M., Iida S., Kitajima T., Kamanaka Y., Stedeford T., Banasik M., Ueda K.	16181422
(1748) AxCANCre	Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs.	Cancer Sci., 96, 620-6 (2005).	Yanagihara M., Katano M., Takahashi-Sasaki N., Kimata K., Taira K., Andoh T.	16128748
(1476) pBluescript SKII+mIL10	Adenovirus-mediated gene delivery of interleukin-10, but not transforming growth factor beta, ameliorates the induction of Graves' hyperthyroidism in BALB/c mice.	Clin. Exp. Immunol., 141, 405-411 (2005).	Saitoh O., Mizutori Y., Takamura N., Yamasaki H., Kita A., Kuwahara H., Nagayama Y.	16045729
(2726) AxCALacZ (2241) AxCAhp53-F/wt	Adenovirus-mediated p53 gene transfer to the bile duct by direct administration into the bile in a rat cholangitis model.	J. Surg. Res., 128, 126-131 (2005).	Kojima Y., Honda K., Kotegawa H., Kushihata F., Kobayashi N., Liu B., Yokoyama K.K.	16005898
(1204) WEE1Hu	Akt/protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G2/M transition.	Mol. Cell. Biol., 25, 5725-5737 (2005).	Katayama K., Fujita N., Tsuruo T.	15964826
(1245) P450 2B1 (CYP2B1) cDNA	Impaired nuclear translocation of CAR in hepatic preneoplastic lesions: association with an attenuated CYP2B induction by phenobarbital.	FEBS Lett., 579, 3560-3564 (2005).	Numazawa S., Shindo S., Maruyama K., Chibana F., Kawahara Y., Ashino T., Tanaka S., Yoshida T.	15953603
(1678) pAxCAwt	Suppression of Stat3 promotes neurogenesis in cultured neural stem cells.	J. Neurosci. Res., 81, 163-171 (2005).	Gu F., Hata R., Ma Y.J., Tanaka J., Mitsuda N., Kumon Y., Hanakawa Y., Hashimoto K., Nakajima K., Sakanaka M.	15948155
anonymous	A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank.	J. Gene Med., 7, 1148-1157 (2005).	Ugai H., Murata T., Nagamura Y., Ugawa Y., Suzuki E., Nakata H., Kujime Y., Inamoto S., Hirose M., Inabe K., Terashima M., Yamasaki T., Liu B., Nakade K., Pan J., Kimura M., Saito I., Hamada H., Obata Y., Yokoyama K.K.	15945121
(3432) pBlue hNF-IL6 (610 Sal I)	C/EBPalpha functionally and physically interacts with GABP to activate the human myeloid IgA Fc receptor (Fc alphaR, CD89) gene promoter.	Blood, 106, 2534-2542 (2005).	Shimokawa T., Ra C.	15928042
(3121) pAxCAwtit	Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor.	J. Biol. Chem., 280, 28044-28052, (2005).	Ikeno Y., Konno N., Cheon S.H., Bolchi A., Ottonello S., Kitamoto K., Arioka M.	15927955
(1516) pCAmsIL1 alpha	Interference with the IL-1-signaling pathway improves the toxicity profile of systemically applied adenovirus vectors.	J. Immunol., 174, 7310-7319 (2005).	Shayakhmetov D.M., Li Z.Y., Ni S., Lieber A.	15905578
(1681) pCMV (Hu beta) (1870) pCAZ 2	Gene therapy for hepatocellular carcinoma using sonoporation enhanced by contrast agents.	Cancer Gene Ther. 12 (11): 884-889 (2005).	Sakakima, Y., Hayashi, S., Yagi, Y., Hayakawa, A., Tachibana, K., Nakao, A.	15891773
(2726) AxCALacZ	Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts.	J. Biol. Chem., 280, 23041-23047 (2005).	Fujii T., Onohara N., Maruyama Y., Tanabe S., Kobayashi H., Fukutomi M., Nagamatsu Y., Nishihara N., Inoue R., Sumimoto H., Shibasaki F., Nagao T., Nishida M., Kurose H.	15826947
anonymous	Recombinant Virus Bank for gene delivery.	Science, 307, 1722 (2005).	Yokoyama K.K., Murata T, Ugai H., Suzuki E., Terashima M., Kujime Y., Inamoto S., Hirose M., Inabe K., Yamasaki T.	15774743
(1126) pSVtsA58 ori (-)	Functional characterization of a conditionally immortalized mouse epididymis caput epithelial cell line MEPC5 using temperature-sensitive simian virus 40 large T-antigen.	Biochem. Biophys. Res. Commun., 329, 812-823 (2005).	Tabuchi Y, Toyama Y, Toshimori K, Komiyama M, Mori C, Kondo T.	15752729
(2726) AxCALacZ	G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes.	J. Biol. Chem., 280, 18434-18441 (2005).	Nishida M., Tanabe S., Maruyama Y., Mangmool S., Urayama K., Nagamatsu Y., Takagahara S., Turner J.H., Kozasa T., Kobayashi H., Sato Y., Kawanishi T., Inoue R., Nagao T., Kurose H.	15743761
(2726) AxCALacZ (2048) AxE1AdB (1743) AxCAUP (2031) AxE1CAUP (2032) pAxE1CAUP	Effective gene therapy of biliary tract cancers by a conditionally replicative adenovirus expressing uracil phosphoribosyltransferase: significance of timing of 5-fluorouracil administration.	Cancer Res., 65, 546-552 (2005).	Seo E., Abei M., Wakayama M., Fukuda K., Ugai H., Murata T., Todoroki T., Matsuzaki Y., Tanaka N., Hamada H., Yokoyama K.K.	15695398
NIA/NIH mouse 15K cDNA Clone Set	Gene expression profiling of cathepsin D, metallothioneins-1 and -2, osteopontin, and tenascin-C in a mouse spinal cord injury model by cDNA microarray analysis.	Acta. Neuropathol. 109 (2): 165-180. (2005).	Hashimoto, M., Koda, M., Ino, H., Yoshinaga, K., Murata, A., Yamazaki, M., Kojima, K., Chiba, K., Mori, C., Moriya, H.	15592854
(1748) AxCANCre (1750) AxCALNLNZ	Delection of the PDGFR-beta Gene Affects Key Fibroblast Functions Important for Wound Healing	J. Biol. Chem., 280, 9375-9389 (2005).	Gao Z., Sasaoka T., Fujimori T., Oya T., Ishii Y., Sabit H., Kawaguchi M., Kurotaki Y., Naito M., Wada T., Ishizawa S., Kobayashi M., Nabeshima Y., Sasahara M.	15590688
(3021) pCMX-N/RBP-J	Distinct roles of EGF repeats for the Notch signaling system.	Exp. Cell Res., 302, 281-291 (2005).	Sakamoto K., Chao W.S., Katsube K., Yamaguchi A.	15561108

↑ 2004 ↓
RDB No.	Title	Journal	Author	PMID
(1276) pco12 EGFR	Production of soluble mammalian proteins in Escherichia coli: identification of protein features that correlate with successful expression	BMC Biotechnol., 4, 1-18 (2004).	Dyson M.R., Shadbolt S.P., Vincent K.J., Perera R.L., McCafferty J.	15598350
(1210) CDMmMCSFCl7	Induction of mouse c-src in RAW264 cells is dependent on AP-1 and NF-kappaB and important for progression to multinucleated cell formation.	Biochem. Biophys. Res. Commun., 325, 758-768 (2004).	Kumagai N., Ohno K., Tameshige R., Hoshijima M., Yogo K., Ishida N., Takeya T.	15541355
(1675) pxCANCre	An antigen-mediated selection system for mammalian cells that produce glycosylated single-chain Fv.	Biochem. Biophys. Res. Commun., 324, 1165-1172 (2004).	Pihkala P., Kawahara M., Ueda H., Nagamune T.	15504336
(1476) pBluescript SKII+mIL10	Adeno-associated virus vector-mediated interleukin-10 gene transfer inhibits atherosclerosis in apolipoprotein E-deficient mice.	Gene Ther., 11, 1772-1779 (2004).	Yoshioka T., Okada T., Maeda Y., Ikeda U., Shimpo M., Nomoto T., Takeuchi K., Nonaka-Sarukawa M., Ito T., Takahashi M., Matsushita T., Mizukami H., Hanazono Y., Kume A., Ookawara S., Kawano M., Ishibashi S., Shimada K., Ozawa K.	15496963
(1748) AxCANCre	Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle.	J. Cell Biol., 167, 351-363 (2004).	Matsuura K., Wada H., Nagai T., Iijima Y., Minamino T., Sano M., Akazawa H., Molkentin J.D., Kasanuki H., Komuro I.	15492039
(1484) pBluescript SKII+mLIF	Alteration of the timing of implantation by in vivo gene transfer: delay of implantation by suppression of nuclear factor kappaB activity and partial rescue by leukemia inhibitory factor.	Biochem. Biophys. Res. Commun., 321, 886-892 (2004).	Nakamura H., Kimura T., Ogita K., Koyama S., Tsujie T., Tsutsui T., Shimoya K., Koyama M., Kaneda Y., Murata Y.	15358109
(1774) Six4 (M8 type) (1775) Six4 (M18 type) (1776) Six4 (SM type)	Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family.	Mol. Pharmacol., 66, 1325-1331 (2004).	Embry A.C., Glick J.L., Linder M.E., Casey P.J.	15308761
anonymous	Genes for systemic vascular complications are differentially expressed in the livers of type 2 diabetic patients.	Diabetologia, 47, 638-647 (2004).	Takamura T., Sakurai M., Ota T., Ando H., Honda M., Kaneko S.	15298340
(2726) AxCALacZ	Development of donor-specific immunoregulatory T-cells after local CTLA4Ig gene transfer to pancreatic allograft.	Transplantation, 78, 59-64 (2004).	Miao G., Ito T., Uchikoshi F., Akamaru Y., Kiyomoto T., Komodo H., Song J., Nozawa M., Matsuda H.	15257039
(1747) Ad5-dlX	Cell specificity and efficiency of the Semliki forest virus vector- and adenovirus vector-mediated gene expression in mouse cerebellum.	J. Neurosci. Methods, 137, 111-121 (2004).	Sato Y., Shiraishi Y., Furuichi T.	15196833
(1402) AxCAmIL2	Dendritic cell vaccine therapy by immunization with fusion cells of interleukin-2 gene-transduced, spleen-derived dendritic cells and tumour cells.	Scand. J. Immunol., 59, 432-439 (2004).	Ogawa F., Iinuma H., Okinaga K.	15140052
(1748) AxCANCre	Separate control of Rep and Cap expression using mutant and wild-type loxP sequences and improved packaging system for adeno-associated virus vector production.	Mol. Biotechnol., 27, 7-14 (2004).	Mizukami H., Okada T., Ogasawara Y., Matsushita T., Urabe M., Kume A., Ozawa K.	15122043
(1998) AxCAhp21 (2726) AxCALacZ	Induction of CDK inhibitor p21 gene as a new therapeutic strategy against pulmonary fibrosis.	Am. J. Physiol. Lung Cell. Mol. Physiol., 286, L727-L733 (2004).	Inoshima I., Kuwano K., Hamada N., Yoshimi M., Maeyama T., Hagimoto N., Nakanishi Y., Hara N.	15003936
(1402) AxCAmIL2	Gene therapy eradicating distant disseminated micro-metastases by optimal cytokine expression in the primary lesion only: novel concepts for successful cytokine gene therapy.	Int. J. Oncol., 24, 549-558 (2004).	Nagano S., Yuge K., Fukunaga M., Terazaki Y., Fujiwara H., Komiya S., Kosai K.	14767539
(1829) Bombyx POU-M1/SGF-3	Identification of a POU factor involved in regulating the neuron-specific expression of the gene encoding diapause hormone and pheromone biosynthesis-activating neuropeptide in Bombyx mori.	Biochem. J., 380, 255-263 (2004).	Zhang T.Y., Kang L., Zhang Z.F., Xu W.H.	14766018
(1888) pRx-mGMCSF-bsr	Immature dendritic cells reduce proinflammatory cytokine production by a coculture of macrophages and apoptotic cells in a cell-to-cell contact-dependent manner.	J. Leukoc. Biol., 75, 865-873 (2004).	Takahashi M., Kurosaka K., Kobayashi Y.	14761936
(1892) pSK II+[X-K]nbK20	Model of unidirectional transluminal gene transfer.	Mol. Ther., 9, 305-310 (2004).	Arap MA, Lahdenranta J, Hajitou A, Marini FC 3rd, Wood CG, Wright KC, Fueyo J, Arap W, Pasqualini R.	14759814
(1890) pRx-crmA-bsr	Xenopus death receptor-M1 and -M2, new members of the tumor necrosis factor receptor superfamily, trigger apoptotic signaling by differential mechanisms.	J. Biol. Chem., 279, 7629-7635 (2004)	Tamura K., Noyama T., Ishizawa YH., Takamatsu N., Shiba T., Ito M.	14668340
(3211) AxCANLacZ (3343) AxCAEGFP (forward)	A simple method for the simultaneous detection of E1A and E1B in adenovirus stocks.	Oncol. Rep., 11, 173-178 (2004).	Suzuki E., Murata T., Watanabe S., Kujime Y., Hirose M., Pan J., Yamazaki T., Ugai H., Yokoyama K.K.	14654922
(1127) pHSP90	S100A1 is a novel molecular chaperone and a member of the Hsp70/Hsp90 multichaperone complex.	J. Biol. Chem., 279, 4221-4233 (2004).	Okada M., Hatakeyama T., Itoh H., Tokuta N., Tokumitsu H., Kobayashi R.	14638689
(1748) AxCANCre	Stress induces mitochondria-mediated apoptosis independent of SAPK/JNK activation in embryonic stem cells.	J. Biol. Chem., 279, 1621-1626 (2004).	Nishitai G., Shimizu N., Negishi T., Kishimoto H., Nakagawa K., Kitagawa D., Watanabe T., Momose H., Ohata S., Tanemura S., Asaka S., Kubota J., Saito R., Yoshida H., Mak T.W., Wada T., Penninger J.M., Azuma N., Nishina H., Katada T.	14585831
(2726) AxCALacZ (2241) AxCAhp53-F/wt	Adenovirus-mediated p53 gene transfer to the biliary tract in a rat cholangitis model.	J. Japan Biliary Assoc., 18, 174-181 (2004).	Kojima Y., Honda K., Yokoyama K.K, Kushihata F., Kobayashi N.

↑ 2003 ↓
RDB No.	Title	Journal	Author	PMID
(1463) pMFG rat GM-CSF	Thyroid cancer immuno-therapy with retroviral and adenoviral vectors expressing granulocyte macrophage colony stimulating factor and interleukin-12 in a rat model.	Clinical Endocrinol., 59, 734-742 (2003).	Tanaka K., Towata S., Nakao K., Mizuguchi H., Hayakawa T., Niwa M., Ishii N., Nagayama Y.	14974915
(1622) Human PAF receptor	Effects of rhinovirus infection on the adherence of Streptococcus pneumoniae to cultured human rirway epithelial cells.	J. Infect. Dis., 188, 1928-1939 (2003).	Ishizuka S., Yamaya M., Suzuki T., Takahashi H., Ida S., Sasaki T., Inoue D., Sekizawa K., Nishimura H., Sasaki H.	14673774
(5953) pCM-TK	Inducible liver injury in the transgenic rat by expressing liver-specific suicide gene.	Biochem. Biophys. Res. Commun., 311, 920-928 (2003).	Kawasaki M., Fujino M., Li X.K., Kitazawa Y., Funeshima N., Takahashi R., Ueda M., Amano T., Hakamata Y., Kobayashi E.	14623269
(1746) Ax1w1	Gene transfer of a cell cycle modulator exerts anti-inflammatory effects in the treatment of arthritis.	J. Immunol., 171, 4913-4919 (2003).	Nonomura Y., Kohsaka H., Nagasaka K., Miyasaka N.	14568973
(1864) cDNA library of mixed- stage C. elegans for yeast two-hybrid screening	Involvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarity.	BMC Dev. Biol., 3, 8 (2003).	Nonomura Y., Kohsaka H., Nagasaka K., Miyasaka N.	14527340
(1748) AxCANCre	Immortalization of bone marrow-derived human mesenchymal stem cells by removable simian virus 40T antigen gene: analysis of the ability to support expansion of cord blood hematopoietic progenitor cells.	Int. J. Oncol., 23, 925-32 (2003).	Nishioka K., Fujimori Y., Hashimoto-Tamaoki T., Kai S., Qiu H., Kobayashi N., Tanaka N., Westerman K.A, Leboulch P., Hara H.	12963970
(1746) Ax1w1	E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer.	Cancer Res., 63, 4434-4440 (2003).	Fukuda K., Abei M., Ugai H., Seo E., Wakayama M., Murata T., Todoroki T., Tanaka N., Hamada H., Yokoyama K.K.	12907616
(1739) Ax1 CI hp40ip35	Adenoviral interleukin-12 gene transduction into human bronchial epithelial cells: up-regulation of pro-inflammatory cytokines and its prevention by corticosteroids.	Clin. Exp. Allergy., 33, 921-929 (2003).	Ogawa H., Nishimura N., Nishioka Y., Azuma M., Yanagawa H., Sone S.	12859448
(2726) AxCALacZ	Effect of an adenoviral vector that expresses the canine p53 gene on cell growth of canine osteosarcoma and mammary adenocarcinoma cell lines.	Am. J. Vet. Res., 64, 880-888 (2003).	Yazawa M., Setoguchi A., Hong S.H., Uyama R., Nakagawa T., Kanaya N., Nishimura R., Sasaki N., Masuda K., Ohno K., Tsujimoto H.	12856773
(1748) AxCANCre	Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation.	Biochem. J., 375, 365-371 (2003).	Furuyama T., Kitayama K., Yamashita H., Mori N.	12820900
(1127) pHSP90	Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox.	Biochem. J., 374, 433-441 (2003).	Okada M., Itoh H., Hatakeyama T., Tokumitsu H., Kobayashi R.	12803546
(1372) Human MDR1 cDNA	Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities.	Biochem. Pharmacol., 65, 1843-1852 (2003).	Morita N., Yasumori T., Nakayama K.	12781336
(1419) AxCAmGM-CSF	Insight into antibody responses induced by plasmid or adenoviral vectors encoding thyroid peroxidase, a major thyroid autoantigen.	Clin. Exp. Immunol., 132, 408-415 (2003).	Guo J., Pichurin P., Nagayama Y., Rapoport B., McLachlan S.M.	12780686
(917) pAxcw anonymous	Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer.	Am. J. Pathol., 162, 1807-1815 (2003).	Furukawa T., Sunamura M., Motoi F., Matsuno S., Horii A.	12759238
(1727) Ax1 CA gfp	Expression of the coxackievirus and adenovirus receptor in musculoskeletal tumors and mesenchymal tissues: efficacy of adenoviral gene therapy for osteosarcoma.	Cancer Sci., 94, 70-75 (2003).	Kawashima H., Ogose A., Yoshizawa T., Kuwano R., Hotta Y., Hotta T., Hatano H., Kawashima H., Endo N.	12708477
(1748) AxCANCre	Adenovirus-mediated gene transfer of interferon alpha improves dimethylnitrosamine-induced liver cirrhosis in rat model.	Gene Ther., 10, 765-773 (2003).	Suzuki K., Aoki K., Ohnami S., Yoshida K., Kazui T., Kato N., Inoue K., Kohara M., Yoshida T.	12704415
(1679) pCALwL	Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness.	Hum. Mol. Genet., 12, 995-1004 (2003).	Kudo T., Kure S., Ikeda K., Xia A.P., Katori Y., Suzuki M., Kojima K., Ichinohe A., Suzuki Y., Aoki Y., Kobayashi T., Matsubara Y.	12700168
(2726) AxCALacZ	Recombinant adenovirus vector bearing antisense macrophage migration inhibitory factor cDNA prevents acute lipopolysaccharide-induced liver failure in mice.	Lab. Invest., 83, 561-570 (2003).	Iwaki T., Sugimura M., Nishihira J., Matsuura T., Kobayashi T., Kanayama N.	12695559
(1740) Ax1 CI-hp53 (L)	E2FBP1/DRIL1, an AT-Rich Interaction Domain-Family Transcription Factor, Is Regulated by p53.	Mol. Cancer Res., 1, 438-444 (2003).	Ma K., Araki K., Ichwan S.J., Suganuma T., Tamamori-Adachi M., Ikeda M.A.	12692263
(1473) pBluescript KS+mIL4	Prevention of autoantibody-mediated Graves'-like hyperthyroidism in mice withIL-4, a Th2 cytokine.	J. Immunol., 170, 3522-3527 (2003).	Nagayama Y., Mizuguchi H., Hayakawa T., Niwa M., McLachlan S.M., Rapoport B.	12646613
(2726) AxCALacZ	Differential Requirement of G{alpha}12, G{alpha}13, G{alpha}q, and G{beta gamma} for Endothelin-1-Induced c-Jun NH2-Terminal Kinase and Extracellular Signal-Regulated Kinase Activation.	Mol. Pharmacol., 63, 478-488 (2003).	Arai K., Maruyama Y., Nishida M., Tanabe S., Takagahara S., Kozasa T., Mori Y., Nagao T., Kurose H.	12606754
(1257) p40 BamH I-A	Reduction of Natural Adenovirus Tropism to the Liver by both Ablation of Fiber-Coxsackievirus and Adenovirus Receptor Interaction and Use of Replaceable Short Fiber.	J. Virol., 77, 2512-2521 (2003).	Nakamura T., Sato K., Hamada H.	12551989
(2547) AxCAHSVtk (1678) pAxCAwt	Spontaneous mutations in the human gene for p53 in recombinant adenovirus during multiple passages in human embryonic kidney 293 cells.	Biochem. Biophys. Res. Commun., 300, 448-456. (2003).	Ugai H., Suzuki E., Inabe K., Murata T., Hamada H., Yokoyama K.K.	12504105
(2547) AxCAHSVtk (1579) AxCEAprZ (1578) AxCEAprTK	An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice.	Hepatology, 37, 155-163 (2003).	Terazaki Y., Yano S., Yuge K., Nagano S., Fukunaga M., Guo Z.S., Komiya S., Shirouzu K., Kosai K.	12500200

↑ 2002 ↓
RDB No.	Title	Journal	Author	PMID
(1297) pJac-1 (1300) pBSKS-FosB	A homogeneous and noncompetitive immunoassay based on the enhanced fluorescence resonance energy transfer by leucine zipper interaction.	Anal Chem., 74: 5786-5792 (2002).	Ohiro Y., Arai R., Ueda H., Nagamune T.	12463362
(2726) AxCALacZ	Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy.	Circ. Res., 91, 961-969 (2002).	Maruyama Y., Nishida M., Sugimoto Y., Tanabe S., Turner J.H., Kozasa T., Wada T., Nagao T., Kurose H.	12433842
(2726) AxCALacZ	Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cells.	Genes Cells, 7, 1161-1171 (2002).	Nagai-Tamai Y., Mizuno K., Hirose T., Suzuki A., Ohno S.	12390250
(1679) pCALwL	Developmental alteration of nerve injury induced glial cell line-derived neurotrophic factor (GDNF) receptor expression is crucial for the determination of injured motoneuron fate.	J. Neurochem., 82, 961-975 (2002).	Honma M., Namikawa K., Mansur K., Iwata T., Mori N., Iizuka H., Kiyama H.	12358802
(2726) AxCALacZ	MAPK-upstream protein kinase (MUK) regulates the radial migration of immature neurons in telencephalon of mouse embryo.	Development, 129, 4483-4495 (2002).	Hirai S., Kawaguchi A., Hirasawa R., Baba M., Ohnishi T., Ohno S.	12223406
(1163) pSV2 proto-ret	Differential expression of multiple isoforms of the ELKS mRNAs involved in a papillary thyroid carcinoma.	Genes Chromosomes Cancer, 35, 30-37 (2002).	Nakata T., Yokota T., Emi M., Minami S.	12203787
(3211) AxCANLacZ	aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization.	J Cell Sci., 115, 3565-3573 (2002).	Suzuki A., Ishiyama C., Hashiba K., Shimizu M., Ebnet K., Ohno S.	12186943
(1694) pCIcc hp53	TNFalpha induces acetylation of p53 but attenuates its transcriptional activation in rheumatoid synoviocytes.	Int. J. Mol. Med., 10, 269-275 (2002).	Nakazawa M., Aratani S., Hatta M., Araya N., Daitoku H., Kawahara K., Watanabe S., Nakamura H., Yoshino S., Fujii R., Fujita H., Fukamizu A., Nishioka K., Nakajima T.	12165799
(3211) AxCANLacZ	Over-expression of PAR-3 suppresses contact-mediated inhibition of cell migration in MDCK cells.	Genes Cells., 7, 581-596 (2002).	Mishima A., Suzuki A., Enaka M., Hirose T., Mizuno K., Ohnishi T., Mohri H., Ishigatsubo Y., Ohno S.	12059961
(3211) AxCANLacZ	Stability of a Recombinant Adenoviral Vector: Optimization of Conditions for Storage, Transport and Delivery	Jpn. J. Cancer Res., 93, 598-603 (2002).	Ugai H., Watanabe S., Suzuki E., Tsutsui-Nakata H., Yokoyama K., Murata T.	12036457
(1748) AxCANCre (1862) pCALNL5	TGFbeta3-induced activation of RhoA/Rho-kinase pathway is necessary but not sufficient for epithelio-mesenchymal transdifferentiation: implications for palatogenesis.	Int. J. Mol. Med., 9, 563-70 (2002).	Kaartinen V., Haataja L., Nagy A., Heisterkamp N., Groffen J.	12011971
(2007) pAxCAhFADD	Characterization of caspase-8L: a novel isoform of caspase-8 that behaves as an inhibitor of the caspase cascade.	Blood, 99, 4070-4078 (2002).	Himeji D., Horiuchi T., Tsukamoto H., Hayashi K., Watanabe T., Harada M.	12010809
(1739) Ax1 CI hp40ip35	Interleukin (IL)-12 gene transduction and expression into human bronchial epithelial cells (BEAS-2B) by adenovirus vector.	J. Med. Invest., 49, 74-82 (2002).	Ogawa H., Nishimura N., Nishioka Y., Azuma M., Yanagawa H., Sone S.	11901765
(5953) pCM-TK	Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase.	Cancer Gene Ther., 9, 236-242 (2002).	Mizuguchi H., Hayakawa T.	11896439
(1524) pCAhMCSF (1687) pCM-hGM	A novel murine model of Graves' hyperthyroidism with intramuscular injection of adenovirus expressing the thyrotropin receptor.	J. Immunol., 168, 2789-2794 (2002).	Nagayama Y., Kita-Furuyama M., Ando T., Nakao K., Mizuguchi H., Hayakawa T., Eguchi K., Niwa M.	11884447
(2726) AxCALacZ (1565) AxCAmKL	Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice.	Proc. Natl. Acad. Sci. U. S. A., 99, 1383-1388 (2002).	Kanatsu-Shinohara M., Ogura A., Ikegawa M., Inoue K., Ogonuki N., Tashiro K., Toyokuni S., Honjo T., Shinohara T.	11818536
(1184) Mouse E-cadherin full length cDNA	Immobilized E-cadherin model can enhance cell attachment and differentiation of primary hepatocytes but not proliferation	Biotechnol. Lett., 24, 1857-1862 (2002).	Nagaoka M., Ise H., Akaike T.

↑ 2001 ↓
RDB No.	Title	Journal	Author	PMID
AxCANCre (1748)	Controlled expansion of human endothelial cell populations by Cre-loxP-based reversible immortalization.	Hum. Gene Ther., 13, 321-334 (2001).	Noguchi H., Kobayashi N., Westerman K.A., Sakaguchi M., Okitsu T., Totsugawa T., Watanabe T., Matsumura T., Fujiwara T., Ueda T., Miyazaki M., Tanaka N., Leboulch P.	11812287
AxCANCre (1748)	Removal of the floxed neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo.	Genesis., 31, 126-129 (2001).	Kaartinen V., Nagy A.	11747203
AxCANCre (1748)	Inflamed glomeruli-specific gene activation that uses recombinant adenovirus with the Cre/loxP system.	J. Am. Soc. Nephrol., 12, 2330-2337 (2001).	Yokoo T., Ohashi T., Utsunomiya Y., Shiba H., Shen J.S., Hisada Y., Eto Y., Kawamura T., Hosoya T.	11675409
AxCALNLNZ (1750)	Inflamed glomeruli-specific gene activation that uses recombinant adenovirus with the Cre/loxP system.	J. Am. Soc. Nephrol., 12, 2330-2337 (2001).	Yokoo T., Ohashi T., Utsunomiya Y., Shiba H., Shen J.S., Hisada Y., Eto Y., Kawamura T., Hosoya T.	11675409
AxCANLacZ (3211)	Inflamed glomeruli-specific gene activation that uses recombinant adenovirus with the Cre/loxP system.	J. Am. Soc. Nephrol., 12, 2330-2337 (2001).	Yokoo T., Ohashi T., Utsunomiya Y., Shiba H., Shen J.S., Hisada Y., Eto Y., Kawamura T., Hosoya T.	11675409
AxCALacZ (2726)	Cre/loxP-based reversible immortalization of human hepatocytes.	Cell Transplant., 10, 383-386 (2001).	Kobayashi N., Noguchi H., Westerman K.A., Watanabe T., Matsumura T., Totsugawa T., Fujiwara T., Leboulch P., Tanaka N.	11549058
AxCANCre (1748)	Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells.	Oncogene, 20, 5225-5231 (2001).	Fukazawa T., Fujiwara T., Uno F., Teraishi F., Kadowaki Y., Itoshima T., Takata Y., Kagawa S., Roth J.A., Tschopp J., Tanaka N.	11526513
Ax1w1 (1746)	Suppression of arthritis by forced expression of cyclin-dependent kinase inhibitor p21(Cip1) gene into the joints.	Int. Immunol., 13, 723-731 (2001).	Nonomura Y., Koike R., Nishio J., Tsubata R., Kohsaka H., Kubota T., Miyasaka N.	11505515
pBluescript KS+mIFN gamma (1482)	Induction of antitumor immunity by transduction of CD40 ligand gene and interferon-gamma gene into lung cancer.	Cancer Gene Ther., 8, 421-429 (2001).	Noguchi M., Imaizumi K., Kawabe T., Wakayama H., Horio Y., Sekido Y., Hara T., Hashimoto N., Takahashi M., Shimokata K., Hasegawa Y.	11498762
pCAmIL12p40 (1415)	Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit.	J. Immunol., 167, 2379-2387 (2001).	Costa G.L., Sandora M.R., Nakajima A., Nguyen E.V., Taylor-Edwards C., Slavin A.J., Contag C.H., Fathman C.G., Benson J.M.	11490028
Human ETB receptor cDNA (1303)	Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit.	J. Immunol., 167, 2379-2387 (2001).	Costa G.L., Sandora M.R., Nakajima A., Nguyen E.V., Taylor-Edwards C., Slavin A.J., Contag C.H., Fathman C.G., Benson J.M.	11490028
Human ETA receptor cDNA (1302)	An unfolded putative transmembrane polypeptide, which can leado endoplasmic reticulum stress, is a substrate of Parkin.	Cell, 105, 891-902 (2001).	Imai Y., Soda M., Inoue H., Hattori N., Mizuno Y., Takahashi R.	11439185
Human ETB receptor cDNA (1303)	An unfolded putative transmembrane polypeptide, which can leado endoplasmic reticulum stress, is a substrate of Parkin.	Cell, 105, 891-902 (2001).	Imai Y., Soda M., Inoue H., Hattori N., Mizuno Y., Takahashi R.	11439185
pAxCAwt (1678)	Overexpression of EC-SOD suppresses endothelial-cell-mediated LDL oxidation.	Biochem. Biophys. Res. Commun., 285, 84-91 (2001).	Takatsu H., Tasaki H., Kim H.N., Ueda S., Tsutsui M., Yamashita K., Toyokawa T., Morimoto Y., Nakashima Y., Adachi T.	11437376
AxCALacZ (2726)	Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport.	J. Clin. Invest., 108, 41-50 (2001).	Ozawa K., Kondo T., Hori O., Kitao Y., Stern D.M., Eisenmenger W., Ogawa S., Ohshima T.	11435456
Ax1 CA gfp (1727)	Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport.	J. Clin. Invest., 108, 41-50 (2001).	Ozawa K., Kondo T., Hori O., Kitao Y., Stern D.M., Eisenmenger W., Ogawa S., Ohshima T.	11435456
AxCANCre (1748)	Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis.	EMBO J., 20, 3333-3341 (2001).	Ohba Y., Ikuta K., Ogura A., Matsuda J., Mochizuki N., Nagashima K., Kurokawa K., Mayer B.J., Maki K., Miyazaki J., Matsuda M.	11432821
pMFGmIL1RA (1440)	Genetically modified bone marrow continuously supplies anti-inflammatory cells and suppresses renal injury in mouse Goodpasture syndrome.	Blood, 98, 57-64 (2001).	Yokoo T., Ohashi T., Utsunomiya Y., Shen J.S., Hisada Y., Eto Y., Kawamura T., Hosoya T.	11418463
pAxCAhMSSP (reverse) (2276)	Genetically modified bone marrow continuously supplies anti-inflammatory cells and suppresses renal injury in mouse Goodpasture syndrome.	Blood, 98, 57-64 (2001).	Yokoo T., Ohashi T., Utsunomiya Y., Shen J.S., Hisada Y., Eto Y., Kawamura T., Hosoya T.	11418463
RBP-J (1801)	A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters.	Mol. Cell Biol., 21, 4337-4346 (2001).	Kitagawa M., Oyama T., Kawashima T., Yedvobnick B., Kumar A., Matsuno K., Harigaya K.	11390662
pMFGmIL12p40 (1447)	Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis.	J. Clin. Invest., 107, 1293-301 (2001).	Nakajima A., Seroogy C.M., Sandora M.R., Tarner I.H., Costa G.L., Taylor-Edwards C., Bachmann M.H., Contag C.H., Fathman C.G.	11375419
Anonymous ()	Identification of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays.	Hepatology, 33, 832-840 (2001).	Shirota Y., Kaneko S., Honda M., Kawai H.F., Kobayashi K.	11283847
AxCANLacZ (3211)	Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures.	J. Cell Biol., 152, 1183-1196 (2001).	Suzuki A., Yamanaka T., Hirose T., Manabe N., Mizuno K., Shimizu M., Akimoto K., Izumi Y., Ohnishi T., Ohno S.	11257119
pAxCAwt (1678)	PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.	Genes Cells, 6, 721-731 (2001).	Yamanaka T., Horikoshi Y., Suzuki A., Sugiyama Y., Kitamura K., Maniwa R., Nagai Y., Yamashita A., Hirose T., Ishikawa H., Ohno S.	11257119
AxCANLacZ (3211)	PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.	Genes Cells, 6, 721-731 (2001).	Yamanaka T., Horikoshi Y., Suzuki A., Sugiyama Y., Kitamura K., Maniwa R., Nagai Y., Yamashita A., Hirose T., Ishikawa H., Ohno S.	11257119
pco12 EGFR (1276)	Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer's V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner.	J. Neurosci., 21, 1902-1910 (2001).	Niikura T., Hashimoto Y., Okamoto T., Abe Y., Yasukawa T., Kawasumi M., Hiraki T., Kita Y., Terashita K., Kouyama K., Nishimoto I.	11245675
Ax1 CI hp40ip35 (1739)	Enhanced efficiency by centrifugal manipulation of adenovirus-mediated interleukin 12 gene transduction into human monocyte-derived dendritic cells.	Hum. Gene Ther., 12, 333-346 (2001).	Nishimura N., Nishioka Y., Shinohara T., Sone S.	11242526
pCALwL (1679)	Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated Cre/loxP system.	Cancer Gene Ther., 8, 36-44 (2001).	Nagayama Y., Nishihara E., Namba H., Yokoi H., Hasegawa M., Mizuguchi H., Hayakawa T., Hamada H., Yamashita S., Niwa M.	11219492
AxCALNLNZ (1750)	Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated Cre/loxP system.	Cancer Gene Ther., 8, 36-44 (2001).	Nagayama Y., Nishihara E., Namba H., Yokoi H., Hasegawa M., Mizuguchi H., Hayakawa T., Hamada H., Yamashita S., Niwa M.	11219492
AxCAmIL1RA (1560)	Genetically modified bone marrow-derived vehicle cells site specifically deliver ananti-inflammatory cytokine to inflamed interstitium of obstructive nephropathy.	J. Immunol. 166, 609-616 (2001).	Yamagishi H., Yokoo T., Imasawa T., Mitarai T., Kawamura T., Utsunomiya Y.	11123344

↑ 2000 ↓
RDB No.	Title	Journal	Author	PMID
AxCANLacZ (3211)	Transfection of the plasma-type platelet-activating factor acetylhydrolase gene attenuates glutamate-induced apoptosis in cultured rat cortical neurons.	Brain Res., 885, 128-132 (2000).	Hirashima Y., Ueno H., Karasawa K., Yokoyama K., Setaka M., Takaku A.	11121539
Ax1w1 (1746)	Transfection of the plasma-type platelet-activating factor acetylhydrolase gene attenuates glutamate-induced apoptosis in cultured rat cortical neurons.	Brain Res., 885, 128-132 (2000).	Hirashima Y., Ueno H., Karasawa K., Yokoyama K., Setaka M., Takaku A.	11121539
AxCALacZ (2726)	G alpha(i) and G alpha(o) are target proteins of reactive oxygen species.	Nature, 408, 492-495 (2000).	Nishida M., Maruyama Y., Tanaka R., Kontani K., Nagao T., Kurose H.	11100733
pMFGmIL10 (1446)	Antigen-specific T cells transduced with IL-10 ameliorate experimentally induced arthritis without impairing the systemic immune response to the antigen.	J. Immunol., 165, 5980-5986 (2000).	Setoguchi K., Misaki Y., Araki Y., Fujio K., Kawahata K., Kitamura T., Yamamoto K.	11067961
Inducible NOS cDNA (1385)	Geranylgeranylacetone stimulates mucin synthesis in cultured guinea pig gastric pit cells by inducing a neuronal nitric oxide synthase.	J. Gastroenterol., 35, 673-681 (2000).	Rokutan K., Teshima S., Kawai T., Kawahara T., Kusumoro K., Mizushima T., Kishi K.	11023038
AxCAmIL10 (1410)	Interleukin-10 gene transfer improves the survival rate of mice inoculated with Escherichia coli.	Crit. Care. Med., 28, 2685-2689 (2000).	Takakuwa T., Endo S., Shirakura Y., Yokoyama M., Tamatani M., Tohyama M., Aozasa K., Inada K.	10966236
Ax1 CA gfp (1727)	Facilitatory roles of novel compounds designed from cyclopentenone prostaglandins on neurite outgrowth-promoting activities of nerve growth factor.	J. Neurochem., 75, 1092-1102 (2000).	Satoh T., Furuta K., Tomokiyo K., Nakatsuka D., Tanikawa M., Nakanishi M., Miura M., Tanaka S., Koike T., Hatanaka H., Ikuta K., Suzuki M., Watanabe Y.	10936191
AxCAmIL12p35 (1414)	Spleen-derived dendritic cells engineered to enhance interleukin-12 production elicit therapeutic antitumor immune responses.	Int. J. Cancer., 87, 665-672 (2000).	Furumoto K., Arii S., Yamasaki S., Mizumoto M., Mori A., Inoue N., Isobe N., Imamura M.	10925360
AxCAmIL12p40 (1417)	Spleen-derived dendritic cells engineered to enhance interleukin-12 production elicit therapeutic antitumor immune responses.	Int. J. Cancer., 87, 665-672 (2000).	Furumoto K., Arii S., Yamasaki S., Mizumoto M., Mori A., Inoue N., Isobe N., Imamura M.	10925360
pCIcc hp53 (1694)	Regulation of Lef-mediated Transcription and p53-dependent Pathway by Associating β-Catenin with CBP/p300	J. Biol. Chem., 275, 35170-35175 (2000).	Miyagishi M., Fujii R., Hatta M., Yoshida E., Araya N., Nagafuchi A., Ishihara S., Nakajima T., Fukamizu A.	10906119
AxCALacZ (2726)	Enhancement of adenovirus-mediated gene transfer into dermal fibroblasts in vitro and in vivo by polyethylene glycol 6000.	J. Dermatol., 27, 244-251 (2000).	Ohsawa T., Nakamura T., Mihara M., Sato K.	10824488
pxCANCre (1675)	Glioma/glioblastoma-specific adenoviral gene expression using the nestin gene regulator.	Gene Ther., 7, 686-693 (2000).	Kurihara H., Zama A., Tamura M., Takeda J., Sasaki T., Takeuchi T.	10800092
P450 2B1 (CYP2B1) cDNA (1245)	Differential suppression of liver-specific genes in regenerating rat liver induced by extended hepatectomy.	J. Hepatol., 32, 636-644 (2000).	Kurumiya Y., Nozawa K., Sakaguchi K., Nagino M., Nimura Y., Yoshida S.	10782913
AxCEAprZ (1579)	The dominant negative H-ras mutant, N116Y, suppresses growth of metastatic human pancreatic cancer cells in the liver of nude mice.	Gene Ther., 7, 518-526 (2000).	Takeuchi M., Shichinohe T., Senmaru N., Miyamoto M., Fujita H., Takimoto M., Kondo S., Katoh H., Kuzumaki N.	10757026
pHSP90 (1127)	Suppression of heat shock protein-70 by ceramide in heat shock-induced HL-60 cell apoptosis.	J. Biol. Chem., 275, 8872-8879 (2000).	Kondo T., Matsuda T., Tashima M., Umehara H., Domae N., Yokoyama K., Uchiyama T., Okazaki T.	10722733
pHSP90 (1127)	Role of c-jun expression increased by heat shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis. Possible involvement of ceramide in heat shock-induced apoptosis.	J. Biol. Chem., 275, 7668-7676 (2000).	Kondo T., Matsuda T., Kitano T., Takahashi A., Tashima M., Ishikura H., Umehara H., Domae N., Uchiyama T., Okazaki T.	10713077
AxCALacZ (2726)	Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes.	Science, 287, 1258-1262 (2000).	Kobayashi N., Fujiwara T., Westerman K.A., Inoue Y., Sakaguchi M., Noguchi H., Miyazaki M., Cai J., Tanaka N., Fox I.J., Leboulch P.	10678831
AxCANCre (1748)	Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes.	Science, 287, 1258-1262 (2000).	Kobayashi N., Fujiwara T., Westerman K.A., Inoue Y., Sakaguchi M., Noguchi H., Miyazaki M., Cai J., Tanaka N., Fox I.J., Leboulch P.	10678831
AxCALNLNZ (1750)	Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons.	Neurochem., 74, 659-668 (2000).	Araki T., Yamada M., Ohnishi H., Sano S., Uetsuki T., Hatanaka H.	10646517
AxCANCre (1748)	Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons.	Neurochem., 74, 659-668 (2000).	Araki T., Yamada M., Ohnishi H., Sano S., Uetsuki T., Hatanaka H.	10646517
Human ETA receptor cDNA (1302)	Endogenously Generated Nitric Oxide by Nitric-Oxide Synthase Gene Transfer Inhibits Cellular Proliferation.	J. Pharmacol. Exp. Ther., 292, 387-393 (2000).	Maeda Y., Ikeda U., Oya K., Shimpo M., Ueno S., Okada K., Saito T., Mano H., Ozawa K., Shimada K.	10604975
Human ETB receptor cDNA (1303)	Endogenously Generated Nitric Oxide by Nitric-Oxide Synthase Gene Transfer Inhibits Cellular Proliferation.	J. Pharmacol. Exp. Ther., 292, 387-393 (2000).	Maeda Y., Ikeda U., Oya K., Shimpo M., Ueno S., Okada K., Saito T., Mano H., Ozawa K., Shimada K.	10604975
Rat TGF beta 1 cDNA (1195)	Dietary docosahexaenoic acid ameliorates, but rapeseed oil and safflower oil accelerate renal injury in stroke-prone spontaneously hypertensive rats as compared with soybean oil, which is associated with expression for renal transforming growth factor-beta, fibronectin and renin.	Biochim. Biophys. Acta., 1483, 101-110 (2000).	Miyazaki M., Takemura N., Watanabe S., Hata N., Misawa Y., Okuyama H.	10601699
pMFGmIL2 (1441)	A speedy method to detect inserted DNA fragment in cell lines transpected with retroviral vectors.	Cytotechnology, 34, 243-252 (2000).	Ding, L-H, Iimura E., Saijo K., Hamada H., Ohno T.

↑ 1999 ↓
RDB No.	Title	Journal	Author	PMID
AxCALacZ (2726)	Adenovirus-mediated gene expression in the septal cells of cirrhotic rat livers.	J. Hepatol., 30, 101-106 (1999).	Nakamura T., Akiyoshi H., Saito I., Sato K.	9927156
pBluescript SKII+mGM-CSF (1469)	DNA immunization with Plasmodium falciparum serine repeat antigexn: regulation of humoral immune response by coinoculation of cytokine expression plasmid.	Parasitol. Int., 48, 27-33 (1999).	Sakai T., Horii T., Hisaeda H., Zhang M., Ishii K., Nakano Y., Maekawa Y., Izumi K., Nitta Y., Miyazaki J., Himeno K.	11269323
pBluescript KS+mIFN gamma (1482)	DNA immunization with Plasmodium falciparum serine repeat antigen: regulation of humoral immune response by coinoculation of cytokine expression plasmid.	Parasitol. Int., 48, 27-33 (1999).	Sakai T., Horii T., Hisaeda H., Zhang M., Ishii K., Nakano Y., Maekawa Y., Izumi K., Nitta Y., Miyazaki J., Himeno K.	11269323
pBluescript KS+mIL4 (1473)	DNA immunization with Plasmodium falciparum serine repeat antigen: regulation of humoral immune response by coinoculation of cytokine expression plasmid.	Parasitol. Int., 48, 27-33 (1999).	Sakai T., Horii T., Hisaeda H., Zhang M., Ishii K., Nakano Y., Maekawa Y., Izumi K., Nitta Y., Miyazaki J., Himeno K.	11269323
AxCAmIL1RA (1560)	Prophylaxis of antibody-induced acute glomerulonephritis with genetically modified bone marrow-derived vehicle cells.	Hum. Gene Ther., 10, 2673-2678 (1999).	Yokoo T., Ohashi T., Utsunomiya Y., Kojima H., Imasawa T., Kogure T., Hisada Y., Okabe M., Eto Y., Kawamura T., Hosoya T.	10566895
AxCALacZ (2726)	Hepatoprotective action of adenovirus-transferred HNF-3gamma gene in acute liver injury caused by CCl4.	FEBS Let., 459, 1-4 (1999).	Nakamura T., Akiyoshi H., Shiota G., Isono M., Nakamura K., Moriyama M., Sato K.	10508906
ETR103 (1198)	Angiotensin II stimulates platelet-derived growth factor-B chain expression in newborn rat vascular smooth muscle cells and neointimal cells through Ras, extracellular signal-regulated protein kinase, and c-Jun N-terminal protein kinase mechanisms.	Circ. Res., 85, 565-574 (1999).	Deguchi J., Makuuchi M., Nakaoka T., Collins T., Takuwa Y.	10506481
964-C-10 ()	Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).	Genes Chromosomes Cancer, 26, 192-202 (1999).	Yagasaki F., Jinnai I., Yoshida S., Yokoyama Y., Matsuda A., Kusumoto S., Kobayashi H., Terasaki H., Ohyashiki K., Asou N., Murohashi I., Bessho M., Hirashima K.	10502316
745-F-8 ()	Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).	Genes Chromosomes Cancer, 26, 192-202 (1999).	Yagasaki F., Jinnai I., Yoshida S., Yokoyama Y., Matsuda A., Kusumoto S., Kobayashi H., Terasaki H., Ohyashiki K., Asou N., Murohashi I., Bessho M., Hirashima K.	10502316
880-G-9 ()	Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).	Genes Chromosomes Cancer, 26, 192-202 (1999).	Yagasaki F., Jinnai I., Yoshida S., Yokoyama Y., Matsuda A., Kusumoto S., Kobayashi H., Terasaki H., Ohyashiki K., Asou N., Murohashi I., Bessho M., Hirashima K.	10502316
638-E-12 ()	Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).	Genes Chromosomes Cancer, 26, 192-202 (1999).	Yagasaki F., Jinnai I., Yoshida S., Yokoyama Y., Matsuda A., Kusumoto S., Kobayashi H., Terasaki H., Ohyashiki K., Asou N., Murohashi I., Bessho M., Hirashima K.	10502316
AxCALacZ (2726)	Adenovirus-mediated transfer of wild-type p53 gene results in apoptosis or growth arrest in human cultured gastric carcinoma cells.	Int. J. Oncol., 15, 229-235 (1999).	Tatebe S., Matsuura T., Endo K., Teramachi K., Nakamura T., Sato K., Ito H.	10402231
Rat HGF cDNA (1194)	Wy-14,643, a peroxisome proliferator, inhibits compensative cell proliferation and hepatocyte growth factor mRNA expression in the rat liver.	Cancer Lett., 135, 145-150 (1999).	Motoki Y., Tamura H., Watanabe T., Suga T.	10096422
P450 2B1 (CYP2B1) cDNA (1245)	Biochemical functions and mRNA expression of rat hepatocytes in a bioartifical liver module.	Yonago Acta medica, 42, 103-112 (1999).	Okada S., Kono Y., Shiraki K.
Ax1 CA gfp (1727)	アデノウイルスベクターを用いたラット上頚神経節細胞への遺伝子導入	脳21, 2, 221-227 (1999).	三浦真紀, 田中秀逸, 小池達郎

↑ 1998 ↓
RDB No.	Title	Journal	Author	PMID
AxCALacZ (2726)	A newly developed adenovirus-mediated transfer of a wild-type p53 gene increases sensitivity to cis-diamminedichloroplatinum (II) in p53-deleted ovarian cancer cells.	Eur. J. Cancer., 34, 1802-1806 (1998).	Kanamori Y., Kigawa J., Minagawa Y., Irie T., Oishi T., Shimada M., Takahashi M., Nakamura T., Sato K., Terakawa N.	9893672
AxCALacZ (2726)	Adenovirus-transferred HNF-3 gamma conserves some liver functions in primary cultured hepatocytes of adult rats.	Biochem. Biophys. Res. Commun., 253, 352-357 (1998).	Nakamura T., Mura T., Saito K., Ohsawa T., Akiyoshi H., Sato K.	9878541
pDBH-1 (1271)	A novel protein containing Cdc10/SWI6 motifs regulates expression of mRNA encoding catecholamine biosynthesizing enzymes.	J. Biol. Chem., 273, 27051-27054 (1998).	Yamakuni T., Yamamoto T., Hoshino M., Song S.Y., Yamamoto H., Kunikata-Sumitomo M., Minegishi A., Kubota M., Ito M., Konishi S.	9765218
pHTH1 (1269)	A novel protein containing Cdc10/SWI6 motifs regulates expression of mRNA encoding catecholamine biosynthesizing enzymes.	J. Biol. Chem., 273, 27051-27054 (1998).	Yamakuni T., Yamamoto T., Hoshino M., Song S.Y., Yamamoto H., Kunikata-Sumitomo M., Minegishi A, Kubota M., Ito M., Konishi S.	9765218
pPCDC13 EcoA (1270)	A novel protein containing Cdc10/SWI6 motifs regulates expression of mRNA encoding catecholamine biosynthesizing enzymes.	J. Biol. Chem., 273, 27051-27054 (1998).	Yamakuni T., Yamamoto T., Hoshino M., Song S.Y., Yamamoto H., Kunikata-Sumitomo M., Minegishi A., Kubota M., Ito M., Konishi S.	9765218
465.2 (1298)	Leptin receptor signal transduction: OBRa and OBRb of fa type.	Biochem. Biophys. Res. Commun., 246, 752-759 (1998).	Yamashita T., Murakami T., Otani S., Kuwajima M., Shima K.	9618284
pHTH1 (1269)	Expression of mRNA coding for four catecholamine-synthesizing enzymes in human adrenal pheochromocytomas.	Eur. J. Endocrinol., 138, 383-387 (1998).	Isobe K., Nakai T., Yukimasa N., Nanmoku T., Takekoshi K., Nomura F.	9578504
c-jun -730, -79 CAT (1362)	Stretch activates jun N-terminal Kinase/Stress-activated protein kinase in vascular smooth muscle cells through mechanisms involving autocrine ATP stimulation of purinoceptors.	J. Biol. Chem., 273, 6334-6340 (1998).	Hamada K., Takuwa N., Yokoyama K., Takuwa Y.	9497362
pBS rcjun-1 (1130)	Stretch activates jun N-terminal Kinase/Stress-activated protein kinase in vascular smooth muscle cells through mechanisms involving autocrine ATP stimulation of purinoceptors.	J. Biol. Chem., 273, 6334-6340 (1998).	Hamada K., Takuwa N., Yokoyama K., Takuwa Y.	9497362

↑ 1997 ↓
RDB No.	Title	Journal	Author	PMID
pGKlacZ (1437)	Development of a novel selective amplifier gene for controllable expansion of transduced hematopoietic cells.	Blood, 90, 3884-3892 (1997).	Ito K., Ueda Y., Kokubun M., Urabe M., Inaba T., Mano H., Hamada H., Kitamura T., Mizoguchi H., Sakata T., Hasegawa M., Ozawa K.	9354655
iNOS 2-2U (1385)	Oxidant-induced activation of nuclear factor-kappa B in cultured guinea pig gastric epithelial cells.	Dig. Dis. Sci.,42, 1880-1889 (1997).	Rokutan K., Teshima S., Miyoshi M., Nikawa T., Kishi K.	9331151
465.2 (1298)	Leptin receptor of Zucker fatty rat performs reduced signal transduction.	Diabetes, 46, 1077-1080 (1997).	Yamashita T., Murakami T., Iida M., Kuwajima M., Shima K.	9166683
human HSP90-alpha ()	Messenger Ribonucleic Acid Expression of Heat Shock Proteins HSP70 and HSP90 in Human Endometrium and Myometrium during the Menstrual Cycle.	J. Clin. Endocrinol. Metabol., 82, 1385-1389 (1997).	Komatsu T., Konishi I., Fukumoto M., Nanbu K., Koshiyama M., Mandai M., Mori T.	9141521
465.2 (1298)	A short form of leptin receptor performs signal transduction.	Biochem. Biophys. Res. Commun., 231, 26-29 (1997).	Murakami T., Yamashita T., Iida M., Kuwajima M., Shima K.	9070213

↑ 1996 ↓
RDB No.	Title	Journal	Author	PMID
pHTH1 (1269)	Pituitary adenylate cyclase-activating polypeptide induces gene expression of the catecholamine synthesizing enzymes, tyrosine hydroxylase and dopamine beta hydroxylase, through 3',5'-cyclic adenosine monophosphate- and protein kinase C-dependent mechanisms in cultured porcine adrenal medullary chromaffin cells.	Neuropeptides., 30, 167-175 (1996).	Isobe K., Yukimasa N., Nakai T., Takuwa Y.	8771559
pDBH-1 (1271)	Pituitary adenylate cyclase-activating polypeptide induces gene expression of the catecholamine synthesizing enzymes, tyrosine hydroxylase and dopamine beta hydroxylase, through 3',5'-cyclic adenosine monophosphate- and protein kinase C-dependent mechanisms in cultured porcine adrenal medullary chromaffin cells.	Neuropeptides., 30, 167-175 (1996).	Isobe K., Yukimasa N., Nakai T., Takuwa Y.	8771559
P450 2B1 (CYP2B1) cDNA (1245)	A cardiotonic steroid bufalin-induced differentiation of THP-1 cells. Involvement of Na+, K(+)-ATPase inhibition in the early changes in proto-oncogene expression.	Biochem. Pharmacol., 52, 321-329 (1996).	Numazawa S., Inoue N., Nakura H., Sugiyama T., Fujino E., Shinoki M., Yoshida T., Kuroiwa Y.	8694857
P450 1A2 (CYP1A2) cDNA (1244)	A cardiotonic steroid bufalin-induced differentiation of THP-1 cells. Involvement of Na+, K(+)-ATPase inhibition in the early changes in proto-oncogene expression.	Biochem. Pharmacol., 52, 321-329 (1996).	Numazawa S., Inoue N., Nakura H., Sugiyama T., Fujino E., Shinoki M., Yoshida T., Kuroiwa Y.	8694857
P450 1A2 (CYP1A2) cDNA (1244)	Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis).	J. Pharmacol. Exp. Ther., 277, 1676-1684 (1996).	Oguro T., Kaneko E., Kaneko Y., Numazawa S., Imaoka S., Funae Y., Mikami T., Yoshida T.	8667238
P450 2B1 (CYP2B1) cDNA (1245)	Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis).	J. Pharmacol. Exp. Ther., 277, 1676-1684 (1996).	Oguro T., Kaneko E., Kaneko Y., Numazawa S., Imaoka S., Funae Y., Mikami T., Yoshida T.	8667238
c-jun -730, -79 CAT (1362)	Detection of living cells that express AP1 using a fluorolabeled DNA probe.	FEBS Lett., 388, 16-20 (1996).	Noriaki Shimokawa, Mitsuhiko Miura	8654580
pBS rcjun-1 (1130)	Detection of living cells that express AP1 using a fluorolabeled DNA probe.	FEBS Lett., 388, 16-20 (1996).	Noriaki Shimokawa, Mitsuhiko Miura	8654580

↑ 1995 ↓
RDB No.	Title	Journal	Author	PMID
Rat TGF beta 1 cDNA (1195)	TSC-36 (follistatin-related polypeptide) gene expression in estrogen receptor positive osteoblastic cell line, CDO7F.	Calcif Tissue Int., 61, 400-403 (1997).	Ohashi T., Sato S., Yoshiki A., Kusakabe M.	9351882
pHTH1 (1269)	Expression of mRNAs coding for catecholamine synthesizing enzymes in human adrenal pheochromocytoma.	Jpn. J. Clin. Pathol., 43, 540-544 (1995).	Isobe K., Yukimasa N., Takekoshi K., Nomura F., Nakai T.	7602797
pDBH-1 (1271)	Expression of mRNAs coding for catecholamine synthesizing enzymes in human adrenal pheochromocytoma.	Jpn. J. Clin. Pathol., 43, 540-544. (1995).	Isobe K., Yukimasa N., Takekoshi K., Nomura F., Nakai T.	7602797
pPCDC13 EcoA (1270)	Expression of mRNAs coding for catecholamine synthesizing enzymes in human adrenal pheochromocytoma.	Jpn. J. Clin. Pathol., 43, 540-544. (1995).	Isobe K., Yukimasa N., Takekoshi K., Nomura F., Nakai T.	7602797
pBS rcjun-1 (1130)	Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells.	J. Biol. Chem., 270, 27326-27331 (1995).	Sawai H., Okazaki T., Yamamoto H., Okano H., Takeda Y., Tashima M., Sawada H., Okuma M., Ishikura H., Umehara H., et al.	7592995

Journal publication

Patent publication

2009
RDB No.	Title	Publication	Applicant (Inventor)
AxCANCre (1748)	Drug Comprising As The Active Ingredient Proliferative Vector Containing Survivin Promoter.	United States Patent Application 20090181907 (2009).	Kamizono, J. (Kagoshima, JP), Nagano, S. (Kagoshima, JP), Kosai, K. (Kagoshima, JP)

2008
RDB No.	Title	Publication	Applicant (Inventor)
pAdexHGF (1553)	Bone Marrow-Related Cells Associated With Tissue Maintenance And/Or Repair.	United States Patent Application 20080038234 (2008).	Hayashi, S. (Nagoya-shi, JP), Inoue, M. (Tsukuba-shi, JP), Hasegawa, M. (Tsukuba-shi, JP)

2007
RDB No.	Title	Publication	Applicant (Inventor)
(1184) Mouse E-cadherin full length cDNA	Pluripotent stem cell growing method.	United States Patent Application 20070155013 (2007).	Akaike, T. (Tokyo, JP), Fukuda, K. (Tokyo, JP), Nagaoka, M. (Kanagawa, JP), Koshimizu, U. (Osaka, JP)

2006
RDB No.	Title	Publication	Applicant (Inventor)
pBluescript SKII+mIL10 (1476)	Blood cholesterol level reducing substance	Patent abstracts of Japan, 2006-028085 (2006).	Shinshu Univ (U. Ikeda, M. Takahashi, T. Yoshioka, T. Ozawa, N. Okada, K. Shimada, K. Maeda, M. Shinpo)
(1184) Mouse E-cadherin full length cDNA	Method of proliferating pluripotent stem cell.	Europian Patent Application, EP-A1-1734112 (2006).	Akaike, T. (Tokyo, JP) Fukuda, K. (Tokyo, JP), Nagaoka, M. (Kanagawa, JP), Koshimizu, U. (Osaka, JP)
2005
(1184) Mouse E-cadherin full length cDNA	Pluripotent stem cell growing method.	Canadian Patent Application, CA 2560581 (2005).	Akaike, T. (Japan) Fukuda, K. (Japan), Nagaoka, M. (Japan), Koshimizu, U. (Japan)
pHSP90 (1127)	Use of geldanamycin and related compounds for treatment of fibrogenic disorders.	United States Patent, US-B2-006887853 (2005).	Strehlow D.
AxCEAprTK (1578) AxCANCre (1748)	Method for efficiently preparing proliferation control type recombinant adenoviral vector and kit for preparing the same vector.	Patent abstracts of Japan, 2005-046101(2005)	Nagoya Industrial Science Research Inst (K. kozai, S. Nagano)
2003
Ax1CAgfp (1727)	Adenovirus adsorption crosslinking agent.	Patent abstracts of Japan, 2003-192700 (2003).	Asahi Kasei Corp (A. Ito, Y. Hanazono, N. Okada, T. Ozawa)
2002
p40 BamH I-A (1257)	Adenovirus vector.	Patent Abstracts of Japan, 2002-330789 (2002).	Hokkaido Technology Licence Office Co Ltd (H. Hamada, T. Nakamura)
AxCANCre (1748)	Reversibly immortalized hepatocytes and methods of use.	United States Patent Application, 20020081283 (2002).	Fox I., LcBoulch P., Kobayashi N.
2001
Ax1w1 (1746)	p21^Cip1 Remedies for rheumatism.	WIPO, WO-A1-001021793 (2001).	N. Miyasaka, H. Kohsaka
1999
Ax1w1 (1746)	Recombinant adenovirus, cosmid vector containing the recombinant virus genom and animal cell infected with the recombinant virus.	Patent abstracts of Japan, H11-332560 (1999)	Oyo seikagaku Kenkyusho (H. Kojima, K. Yagi, S. Oishi)

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2009.12.15