Bioresource Engineering Division

Head
Atsuo Ogura, Ph.D.

The quality of experimental materials determines outcome of research. Bioresource Engineering Division will develop new technologies to improve the quality of resources held in RIKEN BRC. As an initial effort, this division will focus on the methods for nuclear transfer from somatic cells, establishment of various stem cell lines and cryopreservation of embryos and germ cells.

The object of research is to develop techniques for:
Nuclear transfer cloning Embryo/gametes cryopreservation	Microinsemination Establishment of new stem cell lines
Protocol for mouse nuclear transfer	Production of offspring using spermatozoa retrieved from male mice frozen for 15 years
Dead (red)-alive (green) staining of frozen-thawed rabbit spermatozoa (left) and a rabbit blastocyst derived from ICSI using a cryopreserved sperm and a cryopreserved oocyte (right)	Newly established stem cell lines in the Bioresource Engineering Division

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